It is home to major names like Primark, Top Shop and many more.
However it has said goodbye to some big high street names over the years.
Here are some of the shops that used to call Commercial Road home and what they were replaced by.
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Debenhams has closed in Commercial Road, Portsmouth, and plans have been submitted to demolish it. Picture: Chris Moorhouse (161220-26)
Photo: Chris Moorhouse
2. Burton/ Topman
The store which was home to Burton and Topman has shut down. The site remains empty in 2021. Picture: Habibur Rahman
Photo: Habibur Rahman
The Woolworths store on Commercial Road was a hugely popular suggestion. The shop shut in 2009 as the company entered administration.
Photo: Paul Jacobs
4. Primark - replaced Woolworths
Woolworths former neighbour Primark has since expanded and taken over the former favourites space on Commercial Road to make one giant store.
Photo: Sarah Standing