Fire crews were called to the incident in New Road, Fratton, at 12.15pm.
A spokesman for Southsea Fire Station said: '˜The fire started in the lounge on the ground floor of the property.
'˜Smoke travelled next door but nothing there was damaged.'
Fire crews from Southsea, Cosham, Portchester and Havant attended and had left the scene by 1.30pm.
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A spokesman for Hampshire police said: '˜We assisted Hampshire Fire and Rescue Service with road closures.
'˜Nobody was inside the building and no-one was hurt.
'˜The cause of the fire is under investigation.'
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