Gosport Borough suffered a 2-1 defeat to Eastbourne Borough in the Skrill South tonight.
The Privett Park hosts conceded either side of the break before Jamie Brown was sent off.
Dan Wooden did cut the deficit for Borough but, despite Eastbourne also being reduced to 10 men, the home side could not bridge the gap.
They remain bottom of the table – five points adrift of nearest rivals Dorchester.
Elsewhere, Nathan Kirby netted twice as AFC Portchester beat AFC Totton in the Russell-Cotes Cup quarter-final.
Horndean beat Verwood Town 2-0 in the Wessex League premier division courtesy of goals from Nathan Paxton and Dan Martin.