Danny Cowley’s side are out to make it seven wins on the spin against the League Two outfit at Fratton Park.
But how will the Blues boss go as he looks to keep the wins going against Simon Weaver’s men?
We’ve done our digging and come up with what we believe is the like Pompey line-up.
Designed with Pompey fans in mind
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1. FA Cup - Pompey v Harrogate
Pompey turn to FA Cup duty tomorrow against Harrogate. Photo: Catherine Ivill
2. Gavin Bazunu
First choice and no reason he won't continue in goal against Harrogate. Photo: The News
3. Mahlon Romeo
Has momentum which has seen his form fly, so time to get things moving this weekend. Photo: The News
4. Kieron Freeman
Has returned with an air of calm and composure in the back three. Photo: The News