And Danny Cowley’s men will be hoping home comforts will aid them as they bid to end their league goal drought.
It’s 358 minutes since the Blues last scored in League One action, and they are out to avoid equalling their worst barren league run of the 21st century.
We will be building up to the game as Pompey look to end a run of three defeats on the spin, which has seen their strong start to the campaign slow.
Then the team news is in at 2pm with reaction and video from PO4, before we bring you live commentary from 3pm.
Predicted Portsmouth XI v Cheltenham: changes expected to side that beat Cardiff so handsomely - but attacking duo could keep places and defender set to return
Portsmouth transfer news: Blues youngsters attracting interest but Danny Cowley has no desire to cash in just yet
Portsmouth boss Danny Cowley makes transfer admission as former Luton and Millwall midfielder edges closer to Fratton Park exit
Former Portsmouth keeper Alex Bass suffers tough night on and off the pitch as he makes Sunderland debut following Fratton Park exit
League One latest: Oxford land former Pompey striker target from Swansea as Sheffield Wednesday bemoan exciting duo's move to Brentford and former Peterborough boss criticises club
A message from the Editor, Mark Waldron
The News has launched a subscription offer which gives you unlimited access to all of our Pompey coverage, starting at less than 14p a day.
You can subscribe here to get the latest news from Fratton Park - and to support our local team of expert Pompey writers.
FT Pompey 1 Cambridge United 2
Last updated: Saturday, 18 September, 2021, 16:58
- Five changes for Pompey
- Downing, Azeez, Harrison, Curtis and Romeo come in for the injured Robertson, Morrell, Hackett-Fairchild, Marquis and Freeman.
- 38: Ironside heads visitors in front against run of play
- 69: O’Neil doubles visitors’s lead
Game on as Curtis lashes home a ferocious angled half volley to reduce the arrears
Ironside on for Smith
It’s a nightmare for Pompey as Cambridge double their lead from a corner with one heck of a hit from O’Neil outside the box. Bazunu gets fingers too it but the power of the shot sees it into the top corner. ‘This is embarrassing’ sing the Pompey fans.
Downing off for Hirst as Cowley goes for broke
Important header over the bar from Romeo to stop Digby’s header going in
Harrison and Azeez off for Thompson and Marquis
Movement on the Pompey bench
Counter from Pompey as Harrison tries to flick the ball through for Tunnicliffe to tap in but Mitov gets there. Better from Pompey.