Pompey blew away Spurs’ under-21s with a magnificent second-half display to book home advantage in the Checkatrade Trophy’s knockout stages.
Kenny Jackett’s men trailed 1-0 at the break after Phoenix Patterson had given the visitors a 1-0 lead in a lacklustre first half.
Yet the Blues were a very different proposition following the interval, dictating play and developing a cutting edge to claim a 3-2 success.
Andre Green, in his first game back after two months injured, levelled, before goals from substitutes Gareth Evans and Oli Hawkins proved unassailable.
Harvey White’s 90th-minute free-kick generated a closer final scoreline, but Pompey fully deserved their win.
For the Blues, there was also an encouraging debut from academy striker Bradley Lethbridge, featuring for 65 minutes.
Jackett’s men had already qualified from the group stages, yet a third-straight win now earns them a Fratton Park tie when Friday’s draw is made.
Pompey’s boss had made 11 changes to the side which won at Maidenhead in the FA Cup on Saturday, with fringe players and academy youngsters given match minutes.
Before kick-off, the club carried out their Remembrance commemorations, which were impeccably observed by the 3,138 crowd.
The deadlock was broken on 20 minutes. A wonderful pass splitting the Blues’ defence and, when Luke McGee challenged Patterson, the ball ricocheted kindly for the Spurs man, who squeezed it home.
Pompey levelled on 50 minutes, when Burgess flicked Louis Dennis’ corner goalwards and Green forced the ball home at the far post.
Jackett made a triple substitution on 65 minutes with Evans, Hawkins and Matt Clarke replacing Lethbridge, Haji Mnoga and Green.
Within four minutes, Evans handed the Blues the lead, crashing a low right-footed shot from a free-kick after Dennis had been fouled.
Hawkins made it 3-1 on 81 minutes, after David Wheeler pulled the ball back from the right byline and the striker prodded it home from close range.
There was still time for White to flight a free-kick into the top corner, but this was Pompey’s victory.