Pompey hope to put the disappointment of Cheltenham Town behind them as they return to Fratton Park to face Leyton Orient in League One today.
John Mousinho's side missed the opportunity to extend their lead at the top of the table as they fell to a defeat at Whaddon Road. A Tom Bradbury own goal just after the restart put Pompey in front but Liam Sercombe scored twice in four minutes and the Blues could not find a reply.
It's been a week of mixed news at Pompey, with Alex Robertson returning to parent club Manchester City after a hamstring injury cut his time at PO4 short. The Blues have, however, re-signed goalkeeper Matt Macey, who was a free agent after being released by Luton Town in September.
A win is a must now all clubs are back in League One action and with second-place Bolton Wanderers having two games in hand, points on the board are as important as ever right now. One win in five games isn't promotion-winning form and sooner rather than later Pompey need to rediscover their touch.
Leyton Orient are smack back in the middle of the division in 12th and a win for them would only move them as high as 10th, while there are four clubs that could overtake them should they fail to take any points from their travels this weekend.
Here's the latest injury and team news ahead of Pompey v Leyton Orient.
1. Alex Robertson - Out
Pompey were handed the devastating news this week that the Manchester City loanee has probably played his last game for the Blues after he tore a hamstring in training .
2. Tino Anjorin - out
Suffered an injury against Chesterfield in the FA Cup in November and is sidelined until February or March. Photo: Simon Davies/ProSportsImages
3. Zak Swanson - out
Zak Swanson injured his groin in the EFL Trophy and has not played since. He's undergoing a groin operation which has made John Mousinho consider dipping in to the transfer market.
4. Regan Poole - out
Out for the remainder of the campaign after suffering a serious injury against Chesterfield. Photo: Jason Brown/ProSportsImages