And there’s much for boss John Mousinho to ponder, after Tuesday’s Carabao Cup success at Forest Green.
Mousinho made 10 changes from the opening day with his side picking up a 3-1 success, with plenty now pushing for league inclusion.
Here’s how we think Pompey will line up at Brisbane Road.
1. Predicted line-up
Alex Robertson is pushing for inclusion at Leyton Orient. Photo: Jason Brown
2. GK: Will Norris
A solid showing against Bristol Rovers and no reason to suggest he won't continue at Brisbane Road. Photo: Jason Brown
3. RB: Joe Rafferty
Zak Swanson is pushing hard but Rafferty impressed on the opening day and will continue. Photo: Jason Brown
4. RCB: Regan Poole
Poole appears to be leading the way among the centre-back options and will get a starting spot. Photo: Jason Brown