Cheltenham Town provide the opposition as John Mousinho aims to build on a solid start as boss.
After starting with a preferred 4-3-3 formation, the Blues head coach has switched to a 4-2-3-1 in the past two games.
How he goes about tackling the Robins, who play with a back three will be interesting, as will the players employed.
Here’s how we think Pompey will line up.
. Pompey predicted line-up
Pompey were victorious at Cheltenham earlier in the season. Photo: Jason Brown
. GK - Matt Macey
Looking for third clean sheet on the spin and his fifth since joining on loan from Luton. Photo: Jason Brown
. RB - Joe Rafferty
What a reassuring presence the Scouser has been after putting his Pompey injury hell to bed. Photo: Jason Brown
. CB - Sean Raggett
Has the captain's armband but is being pushed hard by Di'Shon Bernard. Photo: Jason Brown
. CB - Ryley Towler
Had a ropey moment at Lincoln missing a routine ball through the middle, but is still massively in credit after a strong start at Pompey. Photo: Jason Brown
. LB - Connor Ogilvie
Denver Hume is finding it hard to displace the super dependable Ogilvie and looks nailed on to continue. Photo: Jason Brown
. CM - Joe Morrell
What a revelation Morrell has been since his World Cup return. If it's a switch back to a 4-3-3 formation there's every chance he'll be handed a sitting role in midfield. Photo: Jason Brown
1. Pompey predicted line-up
Pompey were victorious at Cheltenham earlier in the season. Photo: Jason Brown
2. GK - Matt Macey
Looking for third clean sheet on the spin and his fifth since joining on loan from Luton. Photo: Jason Brown
3. RB - Joe Rafferty
What a reassuring presence the Scouser has been after putting his Pompey injury hell to bed. Photo: Jason Brown
4. CB - Sean Raggett
Has the captain's armband but is being pushed hard by Di'Shon Bernard. Photo: Jason Brown