Vote on The News' predicted Pompey XI
But we want to know whether you agree with our choice?
Paul Cook is set to stick with his favoured 4-2-3-1 formation, with David Forde once again expected to start in goal for the Blues.
The back four is likely to be Gareth Evans (right-back), Christian Burgess (centre-back), Matt Clarke (centre-back) and Enda Stevens (left-back), with Michael Doyle and Danny Rose sitting in front as the two holding midfielders.
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Hide AdGoing forward, Carl Baker (right), Gary Roberts (centre) and Kyle Bennett (left) are likely to be the attacking three behind lone striker Conor Chaplin.
But do you think the sports desk has got it right ahead of the trip to Whaddon Road?
Let us know by taking part in our poll.