Where could Pompey sit in the League One table after this weekend?
Kenny Jackett's troops are currently seventh on 62 points but could leapfrog the fifth-placed Pilgrims (63) with a victory at Home Park.
Meanwhile, Charlton (62) - who occupy the final play-off berth on goal difference - host top-six chasing Scunthorpe United at the Valley.
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Hide AdThe Addicks are looking to bounce back after suffering a 1-0 defeat at AFC Wimbledon on Tuesday.
The Iron (61) will be looking to reignite their play-off charge at Charlton under caretaker boss Nick Daws.
Scunthorpe have won just one of their past 15 fixtures.
Eighth-placed Peterborough United (61) host relegation-battling Rochdale at London Road.