England led 3-0 at the break thanks to goals from Jude Bellingham (35), Bukayo Saka (43) and Raheem Sterling (45+1).
Saka stretched that lead to four on 62 minutes, before Mehdi Taremi scored for Carlos Queiroz’s troops.
Substitutes Marcus Rashford (71) and Jack Grealish (89) added the finishes to a superb attacking display by the Three lions, before Taremi scored again – this time from the penalty spot 13 minutes into stoppage-time – to handed Iran a late consolation.
. DOHA, QATAR - NOVEMBER 21: Raheem Sterling of England celebrates with teammates after scoring their team's third goal during the FIFA World Cup Qatar 2022 Group B match between England and IR Iran at Khalifa International Stadium on November 21, 2022 in Doha, Qatar. (Photo by Julian Finney/Getty Images)
The England players celebrate Raheem Sterling's goal in today's Group B win against Iran. Picture: Julian Finney/Getty Images Photo: Julian Finney
. Jordan Pickford - 7
The Everton keeper had very little to do and could do nothing with both Mehdi Taremi goals for Iran. Picture: Matthias Hangst/Getty Images) Photo: Matthias Hangst
. Kieran Trippier - 7
The Newcastle full-back is such a reliable performer in both defence and attack. Mr Reliable when it comes to England. Picture: Julian Finney/Getty Images Photo: Julian Finney
. John Stones - 6
The game was proving something of a training exercise for the Man City centre-back before some late mistakes, including the foul that allowed Taremi to score from the penalty spot deep into stoppage-time. Picture: Matthias Hangst/Getty Images Photo: Matthias Hangst
1. Jordan Pickford - 7
The Everton keeper had very little to do and could do nothing with both Mehdi Taremi goals for Iran. Picture: Matthias Hangst/Getty Images) Photo: Matthias Hangst
2. Kieran Trippier - 7
The Newcastle full-back is such a reliable performer in both defence and attack. Mr Reliable when it comes to England. Picture: Julian Finney/Getty Images Photo: Julian Finney
3. John Stones - 6
The game was proving something of a training exercise for the Man City centre-back before some late mistakes, including the foul that allowed Taremi to score from the penalty spot deep into stoppage-time. Picture: Matthias Hangst/Getty Images Photo: Matthias Hangst
4. Harry Maguire - 7
(Replaced by Eric Dier on 70 minutes): Put his Manchester United woes behind him and justified place in starting XI with comfortable display. Will be be fit for USA game on Friday after being substituted with head injury in second half? Picture: Clive Brunskill/Getty Images Photo: Clive Brunskill