Boss John Mousinho has some big decisions to make both over formation, after playing a back three at Fleetwood, and whether to start the likes of new boy Myles Peart-Harris after his arrival from Brentford.
Here’s how we think the Blues will go at Vale Park.
9. ACM: Abu Kamara
Thrived coming into a more central role last weekend and looks Pompey's brightest attacking spark at present. Photo: Jason Brown
10. ACM: Tom Lowery
Has returned from injury at a high level. A debate whether his comeback is managed and Myles Peart-Harris is used from off. Photo: Jason Brown
11. CF Colby Bishop
Form is short of what we know the Magic Man can produce. Continues to do the right things, however, making a return to his best inevitable. Photo: Jason Brown
12. Sub 1: Matt Macey
What a back-up to have after his January arrival. Photo: Eddie Keogh