Indoor hospitality, including pubs, restaurants and cafes, have reopened.
Museums, theatres, cinemas, bowling alleys and other entertainment venues are also allowed to open again.
It is the first time in 2021 that they have been able to open, as the city was under tier four restrictions over Christmas prior to the start of the third lockdown.
We have had photographers out and about across Portsmouth and the surrounding towns today.
Here are some of our best photos.
Make sure to click through all the pages of the gallery.
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1. Shagl Osman and manager Khaled Sleman at Cafe Nut
Staff Shagl Osman and manager Khaled Sleman excited to serve indoors in cafe Nut, North End, Portsmouth. Picture: Habibur Rahman Photo: habibur rahman
2. Clive Sutton and Ian Noble shaking hands
Friends veteran Clive Sutton and Ian Noble get together in Cafe Nut, Portsmouth. Picture: Habibur Rahman Photo: habibur rahman
3. Janine Findlay with mum, Wendy Findlay
Janine Findlay with mum, Wendy Findlay at Cafe Nut, North End, Portsmouth. Picture: Habibur Rahman Photo: Habibur Rahman
4. Manager Khaled Sleman excited to serve indoors in cafe Nut
Manager Khaled Sleman excited to serve indoors in cafe Nut, North End, Portsmouth. Picture: Habibur Rahman Photo: Habibur Rahman