John Mousinho’s men are aiming to hit a 23-year second-tier high against a Stoke City side going very well themselves.
So how does Mousinho attack the game as Pompey sign off for the November international break?
Here’s how Blue writer Jordan Cross thinks he will go.
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14. Sub 2 Connor Shaughnessy
Expect fit-again defender to pick up some minutes. | Jason Brown
15. Sub 3 Zak Swanson
Can't see Swanson replacing Devlin, but a closer call with Meghoma. | Jason Brown
16. Sub 4 Ebou Adams
Will either start in the middle, as a 10 or energise off the bench. We've gone for the third option. | Jason Brown
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