Terry Devlin’s suspension for his red card handball at Sheffield United guarantees at least one change, as the Northern Ireland man serves a one-game suspension.
There are many other players whose continuing involvement will be under the microscope, after the weak 3-0 loss at Bramall Lane.
Here’s how Pompey writer Jordan Cross think John Mousinho will go, as his side look to avoid falling into the Championship relegation places.
1. Pompey predicted line-up
Here's how Pompey writer Jordan Cross thinks the Blues will line up against Bristol City. | National World
2. GK Nicolas Schmid
One of the only players whose standing didn't particularly take a hit on Wednesday night, with Austrian certain to continue against Bristol City. | Paul Phelan/ProSportsImages
3. RB Jordan Williams
It's certain to be Williams who replaces the suspended Terry Devlin. The only question would be who goes to right-back and who plays left-back. Williams has switched across to reasonable effect in the past, but we're leaning towards right-back for the man from Yorkshire. | Paul Phelan/ProSportsImages
4. CB Regan Poole
Probably the most nailed on starter in Pompey's squad at present, which says a lot about Poole's importance. Photo: Graham Hunt