Terry Devlin’s suspension for his red card handball at Sheffield United guarantees at least one change, as the Northern Ireland man serves a one-game suspension.
There are many other players whose continuing involvement will be under the microscope, after the weak 3-0 loss at Bramall Lane.
Here’s how Pompey writer Jordan Cross think John Mousinho will go, as his side look to avoid falling into the Championship relegation places.
5. CB Josh Knight
Still searching for consistency, but has to favoured over Hayden Matthews against Emil Riis's physicality Unlikely, but there could be a shout to restore Ibane Bowat to the defence. | Graham Hunt/ProSportsImages
6. LB Zak Swanson
A repeat of the fans' favourite's last Fratton Park appearance is the demand after soaring display last weekend against Millwall. | Paul Phelan/ProSportsImages
7. CM John Swift
Missed a couple of games since illness at Hull. Segecic looks good to start as a 10, so it would be in the double midfield pivot for Swift - and he's fresh after not featuring at all in the last two outings. | Graham Hunt/ProSportsImages
8. CM Andre Dozzell
Cited by John Mousinho for poor decision making on Wednesday night. Time for a driving midfield display at the levels we saw early on in the campaign. Photo: Graham Hunt