The challenge for John Mousinho’s side is to record three wins in a row for the first time this season.
But Marti Cifuentes’ side are a different prospect to the struggling side faced at Loftus Road, with 10 wins from 17 seeing the the Londoners charge away from relegation safety.
There are players returning to fitness like Kusini Yengi and hopefully Freddie Potts, though Callum Lang has been ruled out for the season.
Here’s how we think Mousinho will go, as he hunts down another win to ease relegation concerns.
9. RW Matt Ritchie
Continues to wear the armband and will probably start most games between now and the end of the season, with Kaide Gordon as support. | National World
10. ACM Adil Aouchiche
The Frenchman's time to shine. Now has a clear run in the number 10 role with Callum Lang out for the season - how he steps up will be crucial for Pompey in coming weeks. Photo: Jason Brown
11. LW Josh Murphy
Often looks the man most likely to create an opening, as place among division's players with most assists testifies. | Jason Brown/ProSportsImages
12. CF Colby Bishop
Pompey have their full complement of strikers for just the second time this season - but the Magic Man at the head of the queue by a distance. | Jason Brown/ProSportsImages