The Blues travel north once again, this time to face struggling Shrewsbury, who sit 18th in the table – just four points above the drop zone.
Despite Cowley ringing the changes to name an attacking side against Doncaster, it is expected he will revert to a more familiar line up.
Yet the Pompey boss is once more facing a selection headache, having only 14 senior men in his ranks to choose from.
One of those posers will be at the top of the park, after Aiden O’Brien opened his Blues account on his home debut, while Tyler Walker is yet to score in his first five outings.
We’ve pieced together how we think Pompey could shape-up at the New Meadow tonight.
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Yet the Pompey boss is once more facing a selection headache, having only 14 senior men in his ranks to choose from.
5. RWB: Marcus Harness
Provided good width for Pompey last time out as well as putting in several crosses from the right. Photo: JPIMedia
6. CM: Louis Thompson
Has been in terrific form of late in the centre of midfield and will continue there after suspension of Joe Morrell and Shaun Williams' injury. Photo: The News
7. CM: Ryan Tunnicliffe
Midfield frailties could Tunnicliffe return to the starting lineup for the first time since October. Photo: JPIMedia
8. LWB: Denver Hume
Was a shock to see him dropped last time out and may have to fight Hackett for his place after he shone against Doncaster. Photo: The News